A study has identified that lncRNA is highly upregulated in metastatic triple-negative breast cancer, in which hypomethylation promotes tumor cell proliferation, LN metastasis, and lymphangiogenesis by activating forkhead box k1 (FOXK1)-mediated Akt/mTOR and VEGF-C signaling [94]. Here, FOXK1 is linked to triple-negative breast carcinoma.