KLRK1 and pancreatic neoplasm: Studies reported that anti-mesothelin CAR-NK cells with CXCR2 showed enhanced pancreatic tumor infiltration [28], while NKG2D CAR-NK cells co-expressing CXCR1 showed improved migration and infiltration in xenograft models, resulting in a 20% increase in median survival compared to NKG2D CAR-NK cells lacking CXCR1 [29].