In EBV-associated NPC, Wang et al. showed that in Southern China, the rs2069418 of CDKN2B-AS1, in particular, the CC genotype, was associated with increased NPC risk compared to individuals bearing the heterozygote GC genotype (the cohort comprised 10,472 NPC cases and 6907 control cases). This evidence concerns the gene CDKN2B and nasopharyngeal carcinoma.