GBA1 and Gaucher disease: Gaucher disease (GD), which is subdivided into three different types, is the most prevalent form of sphingolipidoses and is caused by mutations in the GBA gene, which encodes for the lysosomal hydrolase β-Glucocerebrosidase, responsible for the degradation of glucosylceramide into glucose and ceramide [4,8,9,10].