In addition, we additionally included two control groups, dCas9 and dCas9/TET1CD‐scrambled sgRNA, and further confirmed through Western blot and CCK‐8 experiments that under the guidance of sgRNA2 and sgRNA5, the dCas9‐TET1CD demethylation system can specifically and significantly activate BRD7 expression, thereby inhibiting the proliferation of NPC cells (Figure S2). Here, BRD7 is linked to nasopharyngeal carcinoma.