CCK‐8 and colony formation experiments indicated that sgRNA2 and sgRNA5‐guided dCas9‐TET1CD significantly inhibited the proliferation ability and colony formation ability of NPC cells, with the co‐expression group showing an even more pronounced inhibitory effect (Figure 5A,B), as similar to the results obtained with BRD7 overexpression (Figure S4). This evidence concerns the gene BRD7 and nasopharyngeal carcinoma.