Notably, there was no statistically meaningful difference in methylation levels between LV‐dCas9‐TET1CD‐sgRNANC and PBS groups, suggesting that although TET1CD has a certain tumour suppressive effect in NPC tumour model, this effect is broad‐spectrum and not specifically mediated by demethylation of the BRD7 promoter (Figure 9G). The gene discussed is BRD7; the disease is nasopharyngeal carcinoma.