BRD7 and nasopharyngeal carcinoma: In addition, NPC cell lines treated with Decitabine, a strong inhibitor of DNA methyltransferase, with the mechanism of action shown in Figure 2D, exhibited a notable increase in BRD7 mRNA and protein expression levels (Figure 2E,F), along with a significant reduction in the methylation level of the BRD7 promoter and an increase in the unmethylated level (Figure 2G).