In PD-1/PD-L1 associated hypophysitis, reported in 7 out of 10 studies [25-27,29-32], treatment typically involves intravenous corticosteroids with a median dose of 200 mg (range: 50-300 mg), followed by maintenance therapy using low-dose prednisolone or hydrocortisone (2.5-7.5 mg/day). This evidence concerns the gene PDCD1 and hypophysitis.