Ampliseq analysis determined that a partial reduction in DKC1 levels in U251 cells decreased the levels of several snoRNAs/scaRNAs determined to be upregulated in GSC and/or GBM cells, including snorA21, snoRA22, snoRA27, snoRA38, snoRA70, snoRA71A, snoRA71D, scaRNA4, scaRNA11, scaRNA18, and scaRNA22 – Fig. 6B and Table S5. The gene discussed is SNORA21; the disease is glioblastoma.