By setting OR > 1.2 to identify genes significantly positively correlated with CHD, we found that 17 genes—ACAN, CBS, DCTPP1, DTYMK, EDIL3, ELN, F2, IFIT3, ITGB5, ITGB7, NFKB1, PCSK9, PTH1R, SLA2, SORBS1, SPINT3, and TINAGL1—were significantly associated with an increased risk of CHD (Figure 2). This evidence concerns the gene PCSK9 and coronary artery disorder.