ITGB7 and coronary artery disorder: In the first step, we used nine methylation sites of ITGB7 (cg04552292, cg04972065, cg08699196, cg11510999, cg14524975, cg15889057, cg20135711, cg23029655, and cg26689077) as exposure data and CHD as the outcome data, with IVW and p < 0.05 as the screening criteria.