Among the 20 most significantly DEGs in SCE cells, three other genes also fell within 250 kb of a POAG or IOP GWAS variant (none were found near MTAG variants)36: FAM105A (near rs368503, IOP variant, rs31916 POAG variant),37GPM6B (near rs55943282, POAG variant),38 and RASL11B (near rs12433661, POAG variant)35 (Table 3). This evidence concerns the gene RASL11B and open-angle glaucoma.