Interestingly, we found clinical variants, associated with neurodevelopmental disorders, at a subset of lysine residues methylated in this study, including K462 of Heterogeneous nuclear ribonucleoprotein U (HNRNPU-K462), K200 of Electron transfer flavoprotein subunit beta (ETFB-K200), and K55 of Elongation factor 1-alpha 2 (EEF1A2-K55) (Table S3). The gene discussed is EEF1A2; the disease is neurodevelopmental disorder.