The immunosuppressive genes MAN1C1 which increases CTLA4 expression35 and CISH, an active suppressor of TCR signaling36, were also upregulated post-COVID while the myo-inositol transporter gene SLC5A3 linked to NF-κB activation and T cell stimulatory gene IL2Rb were downregulated after infection. The gene discussed is CISH; the disease is infection.