Gonadotrophic hormones such as luteinizing hormone (LH) and follicle-stimulating hormone (FSH), as well as prolactin, estrogen, progesterone, and testosterone aberrant secretions, have been reported to also play a role in PCOS pathogenesis (Wilcox, 2005; Falsetto et al., 2009; Paixao et al., 2017). Here, PLOD1 is linked to polycystic ovary syndrome.