Notably, most upregulated genes (82.8%) were shared between the K14/K5:BRAFV600E and Ivl:BRAFV600E tumours (Fig. 4d), of which 253 were expressed significantly higher in tumours compared to normal skin (log fold change >3 and padj <0.001; Supplementary Data 1). Here, KRT14 is linked to neoplasm.