Further, to verify that YBX1 is a co-acting factor in the SNHG1-induced increase in hFOB activity, PCa exosome uptake by hFOB cells using interfering YBX1 (Fig. 5I), ALP assay and EdU proliferation assay showed that interfering with YBX1 rescued part of the SNHG1-induced increase in hFOB activity (Fig. 5J–L). This evidence concerns the gene SNHG1 and posterior cortical atrophy.