Differentially expressed genes were identified, followed by enrichment analysis and immune cell profiling using CIBERSORTx.<h4>Results</h4>Haemodialysis patients exhibited lower body mass index, a higher prevalence of ischaemic heart disease, elevated C-reactive protein and B-type natriuretic peptide levels, and impaired diastolic function compared to non-HD patients. This evidence concerns the gene CRP and heart disorder.