LRP6 and Oligodontia: This consistency is exemplified by reports such as Ross et al,34 who documented oligodontia alongside broader systemic features attributed to contiguous gene deletions involving LRP6. Similarly, Huang et al32 observed LRP6 individuals carrying the p.Arg857His variant to exhibit variable expressivity, with tooth agenesis ranging from 4 to 10 missing teeth, often accompanied by ectodermal manifestations like sparse hair.