Longitudinal protein levels according to no severe ROP or severe ROP for the top 9 proteins with the lowest Q values are presented in Figure 2A. The 3 proteins with the most prominent interaction between severe ROP and PNA were P-selectin glycoprotein ligand-1 (PSGL-1; Q = 4.0 × 10−7), tPA (Q = 4.0 × 10−7), and the Fas receptor (FAS; Q = 4.9 × 10−7). This evidence concerns the gene FAS and retinopathy of prematurity.