We selected six DplUSE-containing genes (KIF20A, EXT2, CLDN12, MBNL2, MED18, DKC1) from the 31 orthologous genes identified by the bioinformatic script that are common to human, mouse, and zebrafish (listed in Fig. 1D) and that have a relevant physiological function in malignant neoplasms (Fig. 1C). This evidence concerns the gene EXT2 and cancer.