In detail, to evaluate this functional importance of IFNs on activation of the innate immune system in BLCA, we analysed the anti-tumour effects of the type I-interferons IFN-α2 and IFN-β as well as of the type III-interferon IFN-λ1 on the BLCA cell lines SW780 and RT4. This evidence concerns the gene IFNA2 and bladder transitional cell carcinoma.