MT-ND6 and amyotrophic lateral sclerosis: In this report, the homoplasmic m.14484T>C (p.Met64Val) variant of theMT-ND6 gene was shown to coexist with early-onset ALS in an individual.The m.14484T>C/MT-ND6 gene mutation is a common pathogenic variant inLHON, and there have been no previous reports of its association with ALS at thesame locus.