Furthermore, the soluble extracellulardomain of TREM2 impairs microglial/macrophage erythrophagocytosis by inhibitingvacuolar protein sorting 35-mediated CD36 recycling and promoting lysosomaldegradation of non-recycled CD36, ultimately delaying hematoma clearance andworsening neurological deficits [35]. This evidence concerns the gene CD36 and hematoma.