Compared with wild-typeerythrocytes, nude mice injected with CD47 knockout erythrocytes exhibited fasterhematoma resolution, reduced brain edema, and fewer neurological deficits [46].Similarly, anti-CD47 antibodies enhances hematoma clearance, attenuates braininjury and reduces neurological deficits in ICH models [47, 48, 49, 50]. This evidence concerns the gene CD47 and hematoma.