NFKB1 and colitis: Furthermore, the polycyclic phenolic carboxylic acid lithospermic acid, as well as the dimethoxyflavone cirsimaritin, has been shown to protect mice against dextran sulfate sodium‐induced colitis through NF‐κB inhibition and nuclear factor erythroid 2‐related factor 2 (Nrf2) signaling pathway activation [38, 39].