AIH patients with depression presented with higher serum levels of ALT, AST, and IgG and lower serum levels of C3 and C4 than those without depression (p = 0.002, p = 0.005, p < 0.001, p = 0.044, p = 0.003; Table 1 and Table S2). The gene discussed is GPT; the disease is major depressive disorder.