Conversely, the East Asian–specific risk variant p.G2385R in LRRK2 was identified in non-Finnish European, Central Asian, and East Asian populations, with a markedly higher allele frequency in East Asian PD patients (0.05) compared to non-Finnish European PD patients (1.21×10 ) in the WGS dataset, also consistent with prior findings22. This evidence concerns the gene LRRK2 and Parkinson disease.