NPPB and stroke disorder: Medranda et al., for example, reported that baseline BNP levels ≥500 pg/mL were associated with a > 3-fold increased risk of stroke or death at 30 days post-TAVI.7 Similarly, Sørensen et al. demonstrated that NT-proBNP ≥420 pmol/L independently predicted a twofold higher risk of one-year HF hospitalization and all-cause mortality.13