IL6 and myocarditis: Common features include fever, chondritis, pulmonary disease, vasculitis, neutrophilic dermatitis, and macrocytic anaemia.1,2 Treatments include glucocorticoids, anti-IL-6 agents, JAK inhibitors, and azacytidine; stem cell transplantation is the only curative option in selected patients.1 Cardiovascular involvement is rare, but cases of pericarditis, myocarditis, and vasculopathy are reported.3,4 This case illustrates the rare occurrence of third-degree atrioventricular (AV) block caused by myocarditis in VEXAS syndrome and its resolution after initiation of ruxolitinib.