uncovered that NKX2‐1 expression delineates Wingless‐related integration site (Wnt)‐dependent from Wnt‐independent states in lung adenocarcinoma, offering an NKX2‐1‐guided stratification framework to forecast the efficacy of Wnt‐directed therapies [71]. The gene discussed is NKX2-1; the disease is lung adenocarcinoma.