In the field of SCLC, by establishing a comprehensive library of 40 SCLC PDTOs, researchers identified that non‐neuroendocrine subtypes depend on insulin‐like growth factor 1 (IGF‐1) via activation of the Yes‐associated protein (YAP)–activator protein 1 (AP1) axis, while neuroendocrine subtypes are IGF‐1 independent [73]. Here, FOS is linked to small cell lung carcinoma.