At least 2 of the following:Rash or bilateral nonpurulent conjunctivitis or mucocutaneous inflammation signs (oral, hands or feet).Hypotension or shock.Features of myocardial dysfunction, pericarditis, valvulitis, or coronary abnormalities (including ECHO findings or elevated Troponin/NT-pro-BNP),Evidence of coagulopathy (by PT, PTT, elevated D-Dimers).Acute gastrointestinal problems (diarrhea, vomiting, or abdominal pain). This evidence concerns the gene NPPB and pericarditis.