Moreover, the ECAR assay rate of change of the P2RX1 group was significantly higher than that of the control group (Fig. 6f,g), suggesting that the increase in SUP-B15 ATP after P2RX1 overexpression relies on the production of the glycolytic pathway rather than oxidative phosphorylation, which is in line with the theory of high glycolysis in tumor cells. Here, P2RX1 is linked to neoplasm.