P2RX1 and cancer: To verify the association between Overexpression of P2RX1 and good prognosis of tumors, we conducted a pan-cancer analysis using the Cancer Genome Atlas (TCGA) database, and the analysis of RNA-Seq data from 24 types of tumor tissues and their normal tissue samples showed that except for CHOL and HNSC, the P2RX1 expression in various tumors was lower than that of the corresponding normal tissues (Fig. 3a), and Overexpression was associated with a favorable clinical outcome in some tumors, such as BRCA and HNSC (Fig. 3b,c).