We observed an inverse correlation linking PAN3-AS1 expression to the MSI in six neoplasms, namely diffuse large B cell lymphoma (DLBC), COAD, CRC, THYM, STES, and STAD, but a positive relationship in ten tumor types, such as THCA, HNSC, cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), PRAD, LUAD, LUSC, GBM, LGG, SKCM, and CHOL. Here, PAN3 is linked to diffuse large B-cell lymphoma.