In terms of tumor heterogeneity, we observed an inverse correlation linking PAN3-AS1 expression to the MATH in the pan-kidney cohort (KICH+KIRC+KIRP) (KIPAN), acute myeloid leukemia (LAML), PRAD, sarcoma (SARC), KIRC, and BRCA, but a positive correlation in many tumor types, such as STES, ESCA, GBM, LGG, CRC, and COAD. The gene discussed is PAN3; the disease is colorectal carcinoma.