Hyungseok et al. found that overexpression of BATF in CD8+ T cells expressing a CAR promoted the survival and expansion of tumor-infiltrating CAR-T cells, increased the production of effector cytokines, decreased the expression of inhibitory receptors and the exhaustion-associated transcription factor TOX, and supported the generation of long-lived memory T cells that controlled tumor recurrence.100. Here, TOX is linked to neoplasm.