INS and Hyperglycemia: All rats meeting the more than 10.0 mmol/L threshold for hyperglycemia at baseline on challenge days were included in the evaluation of effects during insulin-induced hypoglycemia, which included n = 9 vehicle-treated rats for challenges 1 and 2 and n = 8 rats for challenges 3 and 4 and for SSTR2a-treated rats, n = 10 in challenge 1, n = 9 in challenge 2 and 3, and n = 7 in challenge 4.