IRF7 and breast neoplasm: However, analysis of scRNAseq breast tumor data (Fig. 1f) showed strong positive correlations between BRRIAR and RIG-I (Spearman’s r = 0.65, p = 2.4e-15) or IRF7 (Spearman’s r = 0.64, p = 2.2e-16; Fig. 6d), suggesting elevated RIG-I signaling in BRRIAR-positive cells.