Compared to healthy controls (1.4 ± 1.5), higher TNSc scores—indicating more severe neuropathy—were not only found in the ataxic group (13.3 ± 4.6; p < 0.001, rrb = 0.97) but also already in pre-ataxic SCA3 mutation carriers (5.7 ± 2.7; p < 0.001, rrb = 0.80). The gene discussed is ATXN3; the disease is neuropathy.