Expanded repeats in the 5' untranslated region of the glutaminase (GLS) gene associated with stage 5 chronic kidney disease (odds ratio (OR) = 14.0 (5.7-34.3, 95% confidence interval (CI))) and liver diseases (OR = 3.0 (1.5-5.9, 95% CI)). This evidence concerns the gene GLS and liver disorder.