The higher levels of ELF3 expression in Her2 subtype breast cancer are consistent with previous studies showing that ELF3 may be a downstream transcription target of Her2 and that there might be a positive feedback loop between them (Neve et al., 2002; Eckel et al., 2003; Coppe et al., 2010). The gene discussed is ELF3; the disease is breast carcinoma.