CXCL10 and cancer: The effect sizes found in this study (CXCL10: OR = 2.12; IL‐6: OR = 3.61) are considered clinically meaningful in epidemiological studies and are comparable to the effect sizes of some established cancer risk factors [40], suggesting that measuring plasma CXCL10 and IL‐6 levels may help improve existing risk stratification models for MGUS progression.