Additionally, TGF‐b as well as stromal cell‐derived factor‐1/CXC chemokine ligand 12 (SDF‐1a/CXCL12) directed migration of adult hematopoietic stem and progenitor cells toward glioma cells in vitro and their homing to experimental gliomas in vivo [179] (Figure 2). This evidence concerns the gene TGFB1 and central nervous system cancer.