ADEM: acute disseminated encephalomyelitis; CSF: cerebrospinal fluid; F: female; IVIG: intravenous immunoglobulin; IVMP: intravenous immunoglobulin; M: male; MMF: mycophenolate mofetil; MOGAD: Myelin oligodendrocyte glycoprotein antibody-associated disease; ON: optic neuritis. The gene discussed is MOG; the disease is acute disseminated encephalomyelitis.