CTSD and infection: MA10 infection induced ten additional down-regulated DEGs (Sparcl1, Slc4a4, Ndrg2, Ptprz1, Slc1a2, Sox9, Aldoc, Serpine2, Cpe, Mt3) and one upregulated DEG (Mbp), while Aβ pathology alone resulted in six down-regulated (Hmgb1, Malat1, Mfge8, Bcan, Mertk, Ptn) and ten up-regulated DEGs (Clu, Gfap, Psen1, Tmsb4x, Vim, Apoe, Aqp4, Ctsd, Dbi, Cd81).