Our study of pathway analysis on the shared downregulated gene set was mainly enriched in “WP3888: VEGFA VEGFR2 signaling,” “GO:0072089: stem‐cell proliferation,” and “G0:0034764: positive regulation of transmembrane transport.” These results provided critical insights into the potential mechanisms by which herpes keratitis might influence the PD, highlighting several pathways that are crucial for cellular maintenance and development. The gene discussed is KDR; the disease is Parkinson disease.