The diagnostic value of GDF15 for T2DM with MS was validated by ROC curve analysis (AUC [95%CI] = 0.793 [0.716–0.870], p < 0.001) with an optimal cut‐off value of 395.81 pg/mL, a sensitivity of 71%, and a specificity of 73%. This evidence concerns the gene GDF15 and myeloid sarcoma.