HER3, an undruggable pseudokinase in the human EGFR family, holds a pivotal role in numerous aggressive human malignancies, especially breast, ovarian, and non-small-cell lung cancers (NSCLC) (Baselga & Swain, 2009; Lee-Hoeflich et al., 2008; Tanner et al., 2006; Vaught et al., 2012). Here, EGFR is linked to non-small cell lung carcinoma.