Immunological escape mechanisms in GBM and meningioma are characterized by low T‐cell infiltration and upregulation of PD‐L1 in tumor cells and peripheral macrophages.[7, 33, 34] To counter these mechanisms, we combined the nanoparticle therapy with systemic delivery of anti‐PD‐1 antibody, aiming to enhance immune cell infiltration and differentiation within the tumor microenvironment. The gene discussed is CD274; the disease is neoplasm.