Prior work has shown that a scarcity of invading T cells, reduction of microglial cytokine expression, and increased expression of PDL1 help tumor cells escape host immune response.[7] To target this mechanism, dendritic cell vaccines, checkpoint inhibitors, CAR T‐cell therapy, and nanoparticle‐mediated delivery of neo‐antigen vaccines or suicide genes have emerged as potential candidates. The gene discussed is CD274; the disease is neoplasm.