ELISA results showed that serum GSH, SOD, GPX4, and SLC3A2 were decreased, and MDA, and ACSL4 were increased in CHF rats, and that Shenfu injection upregulated serum GSH, SOD, GPX4, and SLC3A2 levels and decreased MDA and ACSL4 levels in a dose-dependent manner (Figures 2B–2G). The gene discussed is SOD1; the disease is congestive heart failure.