Functional enrichment showed that these PUS7‐bound transcripts are involved in PI3K–Akt, Ras, Hippo, Wnt, and HIF‐1 signalling, as well as immune‐related processes including T cell differentiation and activation (Figure S14B,C), suggesting that PUS7 promotes NETs formation and M2 macrophage polarization by selectively regulating RNAs that orchestrate tumour‐supportive immune signalling. The gene discussed is AKT1; the disease is neoplasm.