The HER2/CEP17 ratio did not show a statistically significant correlation with the metrical variables age, tumor size, HR status, histologic grade, histologic subtype, or menopausal status (Table 2), it did, however, show a weak correlation with the percentage of invasive tumor cells with complete membrane staining (i.e. 3+; Pearson's correlation coefficient r = 0.26, p = 0.0036) (Supplementary Fig. 1). Here, ERBB2 is linked to neoplasm.