Significant intergroup disparities emerged across multiple domains: age, sex, race, education level, poverty index, BMI, HbA1c, FTUs, diabetes status, hyperlipidemia, alkaline phosphatase, albumin, lymphocyte count, monocyte count, neutrophil count, SII, hemoglobin, creatinine, smoking status, alcohol consumption, PHQ-9-scores, CKD and coronary heart disease. The gene discussed is ALB; the disease is chronic kidney disease.