Nevertheless, mixed and heterogeneous regions were observed, particularly in low- to mid-level ENPP1 expression, and low HRD score range where prostate adenocarcinoma, colon adenocarcinoma, rectum adenocarcinoma, cervical squamous cell carcinoma, and kidney renal clear cell carcinoma were the predominant tumor types. This evidence concerns the gene ENPP1 and rectum adenocarcinoma.