ETV3 and chronic kidney disease: CKD risk approached significance (moderate/high vs low: HR = 1.04, 95% CI: 1.01–1.07, P = .010; P-interaction = .071), while MeTS absence was unexpectedly associated with increased risk (HR = 1.03, 95% CI: 1.00–1.07, P = .041) despite non-significant interaction (P-interaction = .449).